circRNA basic information
circBase ID: hsa_circ_0008583
Name: hsa_circ_DLG1
Synonym: circ_0008583
Host Gene: hsa-miR-1301-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human normal hepatocytes (LO2), hepatoma cell lines (Hep3B, Huh-7)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1301-3p
Biological function: Hsa_circ_0008583 overexpression promoted Hep3B cell proliferation, migration and invasion, but hsa_circ_0008583 silencing had an opposing influence.
Molecular mechanism: hsa-miR-1301-3p is directly bound to hsa_circ_0008583 and METTL3.
Survival: -
Supported No.:
 3
Description:

In conclusion, hsa_circ_0008583 promotes HCC progression through the miR-1301-3p/METTL3 axis.
Other information
Title:

Has_circ_0008583 modulates hepatocellular carcinoma progression through the miR-1301-3p/METTL3 pathway.

Journal: Bioengineered
Published: 2022/3/9
PubMed ID: 35258395