circRNA basic information
circBase ID: hsa_circ_0007360
Name: -
Synonym: circ0007360
Host Gene: hsa-miR-762
 
 
 
Disease basic information
DO ID:
10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human gastric cancer cell lines (AGS, MKN-7)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-762
Biological function: In vivo_xperiments confirmed the potentiation of gastric cancer cell growth and stemness upon depletion of_irc0007360.
Molecular mechanism: Interferon regulatory factor 7 (IRF7), which was validated as a target gene of_iR-762, serves as an indirect target ofcirc0007360
Survival: -
Supported No.:
1
Description:

In summary, our results revealed that activation of the_irc0007360/miR-762/IRF7_xis is a novel mechanism for the attenuation of gastric cancer progression. Our study unveils the diagnostic and therapeutic values of_irc0007360_n patients with gastric cancer.

Other information
Title:

Circular RNA circ0007360 Attenuates Gastric Cancer Progression by Altering the miR-762/IRF7 Axis.

Journal: Front Cell Dev Biol
Published: 2022/3/8
PubMed ID: 35252169