circRNA basic information
circBase ID: -
Name: hsa_circ_PTK2
Synonym: CircPTK2
Host Gene: hsa-miR-942
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A549/CDDP, H1299/CDDP cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-942
Biological function: Everexpression of circPTK2 remarkably inhibited cell growth, metastasis, and glycolysis in A549/CDDP and H1299/CDDP cells.
Molecular mechanism: circPTK2 weakened CDDP resistance of NSCLC through modulating hsa-miR-942/TRIM16 axis
Survival: -
Supported No.:
 3
Description:

circPTK2 weakened CDDP resistance of NSCLC through modulating miR-942/TRIM16 axis, providing a novel sight for the treatment of NSCLC and improving the understanding of the CDDP resistance mechanism of NSCLC.
Other information
Title:

CircPTK2 inhibits cell cisplatin (CDDP) resistance by targeting miR-942/TRIM16 axis in non-small cell lung cancer (NSCLC).

Journal: Bioengineered
Published: 2022/3/2
PubMed ID: 35230201