circRNA basic information
circBase ID: hsa_circ_0048856
Name: -
Synonym: circ_0048856
Host Gene: hsa-miR-1287-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human bronchial epithelial cell (HBE), NSCLC cells (A549, H1299, SK-MES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1287-5p
Biological function: promote cells proliferation, invasion and migration while inhibit cells apoptosis
Molecular mechanism: downregulate hsa-miR-1287-5p, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Exosomes derived circ_0048856 was elevated in NSCLC serum and cell lines. Exosome circ_0048856 promoted the NSCLC development by targeting miR-1287-5p. Exosome circ_0048856 had high diagnostic value for NSCLC.
Other information
Title:

Exosomal circ_0048856 derived from non-small cell lung cancer contributes to aggressive cancer progression through downregulation of miR-1287-5p.

Journal: Pathol Res Pract
Published: 2022/3/2
PubMed ID: 35228162