circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circRNA_102049
Host Gene: hsa-miR-455-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A normal human intestinal epithelium cell line (NCM460), CRC cell lines (SW480, LOVO, HT29, DLD-1, SW620, HCT116), 293T cell line
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-455-3p
Biological function: associated with enhanced CRC cell proliferation, migration and invasion.
Molecular mechanism: hsa_circRNA_102049 knockdown significantly increased hsa-miR-455-3p expression
Survival: -
Supported No.:
 1
Description:

The present study clearly demonstrated that miRNA-455-3p was a target of hsa_circRNA_102049. Moreover, the results indicated that the circular RNA, hsa_circRNA_102049, may function as a tumor promoter in CRC via directly sponging miRNA-455-3p.
Other information
Title:

Circular RNA, hsa_circRNA_102049, promotes colorectal cancer cell migration and invasion via binding and suppressing miRNA-455-3p.

Journal: Exp Ther Med
Published: 2022/3/1
PubMed ID: 35222721