circRNA basic information
circBase ID: hsa_circ_0003221
Name: hsa_circ_PTK2
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: bladder cancer cell lines cells (T24, 5637)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes the proliferation and migration of bladder cancer cells
Molecular mechanism: -
Survival: -
Supported No.:
4
Description:

In vitro silence of circPTK2 by small interfering RNA inhibited the proliferation and migration of bladder cancer cells. On the contrary, circPTK2 overexpression promoted proliferation and migration.

Other information
Title:

Circular RNA hsa_circ_0003221 (circPTK2) promotes the proliferation and migration of bladder cancer cells.

Journal: J Cell Biochem
Published: 2017/11/11
PubMed ID: 29125888