circRNA basic information
circBase ID: hsa_circ_0067934
Name: -
Synonym: circRNA_0067934
Host Gene: hsa-miR-7
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HEK 293T, glioma cell lines (U87, U251)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-7
Biological function: down regulation of circRNA_0067934 reduced the tumor progression by inhibiting cell proliferation, invasion, and migration.
Molecular mechanism: CircRNA_0067934 could tagete the hsa-miR-7 to regulate progression of glioma cell. In addition, the Wnt/beta-catenin signaling pathway might involve in down stream regulation of circRNA_0067934 and hsa-miR-7.
Survival: -
Supported No.:
 2
Description:

In conclusion, our results revealed that circRNA_0067934 regulates glioma cells progression by targeting miR-7/ Wnt/beta-catenin axis.
Other information
Title:

Circular RNA circRNA_0067934 promotes glioma development by modulating the microRNA miR-7/ Wnt/beta-catenin axis.

Journal: Bioengineered
Published: 2022/2/26
PubMed ID: 35213267