circRNA basic information
circBase ID: hsa_circ_0119412
Name: hsa_circ_PER2
Synonym: -
Host Gene: hsa-miR-1298-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human gastric epithelial cell line (GES-1), GC cell lines (MKN74, GES-1, HGC-27, GTL-16)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1298-5p
Biological function: Both the knockdown of hsa_circ_0119412/ZBED3 and_iR-1298-5p_verexpression inhibited GC cell growth and invasion, and enhanced cell apoptosis, while_iR-1298-5p_nterference or_BED3_verexpression showed the opposite trend.
Molecular mechanism: hsa_circ_0119412 sponges_iR-1298-5p, which regulates ZBED3 expression.
Survival: -
Supported No.:
 1
Description:

hsa_circ_0119412 sponges_iR-1298-5p, which regulates ZBED3 expression. Silencing hsa_circ_0119412 inhibits the progression of GC, at least in part, by targeting the_iR-1298-5p/ZBED3 axis.
Other information
Title:

Circular RNA hsa_circ_0119412 contributes to tumorigenesis of gastric cancer via the regulation of the miR-1298-5p/zinc finger BED-type containing 3 (ZBED3) axis.

Journal: Bioengineered
Published: 2022/2/25
PubMed ID: 35200111