circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: circHIPK3
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3978
DO name: extrinsic cardiomyopathy
Disease details: diabetic cardiomyopathy
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: AC16 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: regulating the apoptosis
Molecular mechanism: Overexpression of circHIPK3 decreased the expression levels of PTEN.
Survival: -
Supported No.:
 1
Description:

Therefore, circHIPK3 may downregulate PTEN to protect cardiomyocytes from high glucose-induced cell apoptosis.
Other information
Title:

Circular RNA circHIPK3 is downregulated in diabetic cardiomyopathy and overexpression of circHIPK3 suppresses PTEN to protect cardiomyocytes from high glucose-induced cell apoptosis.

Journal: Bioengineered
Published: 2022/2/25
PubMed ID: 35200097