circRNA basic information
circBase ID: hsa_circ_0009910
Name: -
Synonym: circ_0009910
Host Gene: hsa-miR-449a
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human OS cell lines (MG63, Saos-2, U2OS), fetal osteoblastic cell line (hFOB)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-449a
Biological function: cell proliferation and inhibiting cell apoptosis
Molecular mechanism: circ_0009910 acted as a sponge of hsa-miR-449a and upregulated hsa-miR-449a functional target IL6R
Survival: -
Supported No.:
 1
Description:

we suggested that circ_0009910 acted as a sponge of miR-449a and upregulated miR-449a functional target IL6R, thereby contributed to carcinogenesis of OS.
Other information
Title:

Hsa_circ_0009910 promotes carcinogenesis by promoting the expression of miR-449a target IL6R in osteosarcoma.

Journal: Biochem Biophys Res Commun
Published: 2017/11/9
PubMed ID: 29117539