circRNA basic information
circBase ID: hsa_circ_0010235
Name: -
Synonym: Circ_0010235
Host Gene: hsa-miR-636
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human bronchial epithelial cells (HBE), lung cancer cell lines (Calu_3, H1650, A549, H1299)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-636
Biological function: Circ_0010235 knockdown inhibited proliferation, invasion and immune escape and promoted apoptosis of lung cancer cells.
Molecular mechanism: hsa-miR-636 was a target of circ_0010235. PDL1 was a direct target of hsa-miR-636
Survival: -
Supported No.:
 2
Description:

Circ_0010235 knockdown inhibited lung cancer progression and increased antitumor immunity by regulating the miR-636/PDL1 axis.
Other information
Title:

Circ_0010235 facilitates lung cancer development and immune escape by regulating miR-636/PDL1 axis.

Journal: Thorac Cancer
Published: 2022/2/16
PubMed ID: 35167195