circRNA basic information
circBase ID: hsa_circ_0002360
Name: -
Synonym: circ_0002360
Host Gene: hsa-miR-6751-3p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Lung cancer cells (A549, H1299), chemoresistant cells (A549/DDP, H1299/DDP)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-6751-3p
Biological function: Silencing circ_0002360 inhibited DDP resistance, proliferation and migration but enhanced apoptosis of DDP-resistant cells.
Molecular mechanism: The regulation of circ_0002360 for ZNF300 was achieved by sponging hsa-miR-6751-3p.
Survival: -
Supported No.:
 2
Description:

Circ_0002360 targeted miR-6751-3p to regulate ZNF300 level, thus elevating DDP resistance and promoting the malignant progression of lung cancer cells.
Other information
Title:

Cisplatin resistance and malignant behaviors of lung cancer cells are promoted by circ_0002360 via targeting miR-6751-3p to regulate the expression of ZNF300.

Journal: Thorac Cancer
Published: 2022/2/16
PubMed ID: 35166026