circRNA basic information
circBase ID: hsa_circ_0139402
Name: hsa_circ_PTCH1
Synonym: circ_0139402
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: UMUC3, UMUC3, 5637, J82, SV-HUC-1
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-326
Biological function: sh-hsa_circ_0139402 could suppress BC cells proliferation, invasion, and migration.
Molecular mechanism: hsa_circ_0139402 can bind to hsa-miR-326, and PAX8 is a direct target of hsa-miR-326 in BC cell.
Survival: -
Supported No.:
 1
Description:

hsa_circ_0139402 plays a oncogene in BC and that can effectively promote cell proliferation, migration, invasion, and EMT by targeting Paired Box Protein Pax-8 (PAX8) via hsa-miR-326 and provides a potential therapeutic target for BC patients.
Other information
Title:

hsa_circ_0139402 Promotes Bladder Cancer Progression by Regulating hsa-miR-326/PAX8 Signaling.

Journal: Dis Markers
Published: 2022/2/15
PubMed ID: 35154515