circRNA basic information
circBase ID: -
Name: hsa_circ_CDK6
Synonym: circCDK6
Host Gene: hsa-miR-449a
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HeLa, CaSki cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-449a
Biological function: the biological function of silencing circCDK6 in cellular proliferation, metastasis, and Epithelial-Mesenchymal Transition (EMT)-related process was determined.
Molecular mechanism: he hsa-miR-449a was further confirmed to be a potential target of circCDK6
Survival: -
Supported No.:
 1
Description:

The circCDK6 participated in tumorigenesis and cancer progression and might serve as a tumor suppressive factor in cervical cell progression via Epithelial-MesenchymalTransition (EMT) process by regulating miR-449a.
Other information
Title:

Circular RNA CDK6 suppresses cervical cancer proliferation and metastasis by sponging miR-449a.

Journal: Bioengineered
Published: 2022/2/15
PubMed ID: 35152839