circRNA basic information
circBase ID: hsa_circ_0001190
Name: -
Synonym: circ_0001190
Host Gene: hsa-miR-586
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human GC cell lines (HGC27, AGS, MKN45, MKN47, N87), with GES-1 cells as control
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-586
Biological function: circ _0001190 overexpression inhibited cell vitality, cell proliferation, angiogenesis, cell migration and invasion, whereas stimulated cell apoptosis in GC cells.
Molecular mechanism: Circ _0001190 served as a hsa-miR-586 sponge to adjust the expression of SOSTDC1.
Survival: -
Supported No.:
 2
Description:

Exosomal circ_0001190 overexpression inhibited the development of GC by miR-586/SOSTDC1 axis, which proposed a potential targeted therapy for GC cure.
Other information
Title:

Exosomal circ_0001190 Regulates the Progression of Gastric Cancer via miR-586/SOSTDC1 Axis.

Journal: Biochem Genet
Published: 2022/2/10
PubMed ID: 35138469