circRNA basic information
circBase ID: -
Name: hsa_circ_CAMSAP1
Synonym: CircCAMSAP1
Host Gene: hsa-miR-1182
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: NSCLC cell lines (A549, H520, H1299, H460), normal human bronchial epithelial cells (NHBE)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1182
Biological function: We also found that downregulated circCAMSAP1 repressed cell proliferation and increased apoptosis of NSCLC cells_n vitro_nd suppressed xenograft tumor growth_n vivo.
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Together, our findings reveal a novel mechanism by which the circCAMSAP1/miR-1182/BIRC5 axis promotes NSCLC progression.
Other information
Title:

CircCAMSAP1 promotes non-small cell lung cancer proliferation and inhibits cell apoptosis by sponging miR-1182 and regulating BIRC5.

Journal: Bioengineered
Published: 2022/2/9
PubMed ID: 35132928