circRNA basic information
circBase ID: -
Name: hsa_circ_STAT346
Synonym: circ-STAT346
Host Gene: hsa-miR-139-5p
 
 
 
Disease basic information
DO ID:
219
DO name: colon cancer
Disease details: colon cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IGF1R
Associated microRNA: hsa-miR-139-5p
Biological function: -
Molecular mechanism: promote expression of IGF1R by sponging of hsa-miR-139-5p
Survival: poor
Supported No.:
1
Description:

circ-STAT3.46 was regulated by IGF/IGF1R/STAT3 activation, and overexpression of circ-STAT3.46 can up-regulate IGF1R by sponging of miR-139-5p within human colon cancer.

Other information
Title:

STAT3 activation regulated circ-STAT346 promote expression of IGF1R by sponging of miR-139-5p in human colon cancer.

Journal: Transl Cancer Res
Published: 2019/11/1
PubMed ID: 35117016