circRNA basic information
circBase ID: hsa_circ_0001947
Name: -
Synonym: circ_0001947
Host Gene: hsa-miR-671-5p
 
 
 
Disease basic information
DO ID:
 848
DO name: arthritis
Disease details: arthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: RA-FLSs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: STAT3
Associated microRNA: hsa-miR-671-5p
Biological function: Knockdown of circ_0001947 repressed cell proliferation, invasion, migration and inflammatory response and facilitated apoptosis in RA-FLSs.
Molecular mechanism: Circ_0001947 served as the sponge for miR-671-5p and the inhibitory effect of circ_0001947 in RA-FLS progression was reversed by miR-671-5p inhibition.
Survival: -
Supported No.:
 1
Description:

Circ_0001947 contributed to the progression of RA-FLSs by elevating STAT3 through adsorbing miR-671-5p.
Other information
Title:

Circ_0001947 promotes cell proliferation, invasion, migration and inflammation and inhibits apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes through miR-671-5p/STAT3 axis.

Journal: J Orthop Surg Res
Published: 2022/1/31
PubMed ID: 35093109