circRNA basic information
circBase ID: hsa_circ_0069117
Name: hsa_circ_TBC1D14
Synonym: -
Host Gene: hsa-miR-875-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human osteosarcoma cell lines (OSCL), U2OS, 143B, MG63, HOS, human mesenchymal stem cell line (hMSCs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-875-3p
Biological function: hsa_circ_0069117 is an anti-OS molecule that could substantially attenuate cell proliferation and migration of OS
Molecular mechanism: hsa_circ_0069117 could significantly promote the expression of PF4V1 by sponging hsa-miR-875-3p
Survival: -
Supported No.:
 1
Description:

hsa_circ_0069117 is an anti-OS molecule that could substantially attenuate cell proliferation and migration of OS, which may provide a novel and reliable molecular target for the treatment of OS patients.
Other information
Title:

Circular RNA hsa_circ_0069117 suppresses proliferation and migration of osteosarcoma cells lines via miR-875-3p/PF4V1 axis.

Journal: J Orthop Surg Res
Published: 2022/1/23
PubMed ID: 35062989