circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-30a
 
 
 
Disease basic information
DO ID:
 0050855
DO name: renal fibrosis
Disease details: renal tubulointerstitial fibrosis
Species: human
Species details: human
Sample type: cell line
Sample type details: Immortalized human renal proximal tubular epithelial cells (HK-2 cells)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-30a
Biological function: exacerbates folic acid-induced renal tubulointerstitial fibrosis
Molecular mechanism: Sponging hsa-miR-30a
Survival: -
Supported No.:
 1
Description:

Our results suggest that circHIPK3 may contribute to progressive renal fibrosis by sponging miR-30a. circHIPK3 may be a novel therapeutic target for slowing CKD progression.
Other information
Title:

circHIPK3 Exacerbates Folic Acid-Induced Renal Tubulointerstitial Fibrosis by Sponging miR-30a.

Journal: Front Physiol
Published: 2022/1/22
PubMed ID: 35058790