circRNA basic information
circBase ID: -
Name: hsa_circ_CARM1
Synonym: circCARM1
Host Gene: hsa-miR-1252-5p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Breast cancer cell lines (MDA-MB-231, MDA-MB-468, BT549, SKBR3, BT474, T47D, MCF7, MCF10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1252-5p
Biological function: Further investigation demonstrated that BCSC exosomes circCARM1 played an important role in breast cancer cell glycolysis
Molecular mechanism: BCSC exosome-derived circCARM1 played an important role in breast cancer cell glycolysis by sponging hsa-miR-1252-5p which regulated PFKFB2 expression.
Survival: -
Supported No.:
 1
Description:

BCSC exosome-derived circCARM1 played an important role in breast cancer cell glycolysis by sponging miR-1252-5p which regulated PFKFB2 expression.
Other information
Title:

Exosomal circCARM1 from spheroids reprograms cell metabolism by regulating PFKFB2 in breast cancer.

Journal: Oncogene
Published: 2022/1/15
PubMed ID: 35027669