circRNA basic information
circBase ID: hsa_circ_0006825
Name: hsa_circ_MED27
Synonym: -
Host Gene: hsa-miR-655-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (Hep3B, Huh7, HepG2, SKHep-1, PLC/PRF/5)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: USP28
Associated microRNA: hsa-miR-655-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

circMED27 acts as a potential therapeutic target for HCC patients receiving lenvatinib therapy and may represent a promising molecular biomarker for forecasting lenvatinib-resistant HCC.
Other information
Title:

circRNA circMED27 acts as a prognostic factor and mediator to promote lenvatinib resistance of hepatocellular carcinoma.

Journal: Mol Ther Nucleic Acids
Published: 2022/1/14
PubMed ID: 35024242