circRNA basic information
circBase ID: -
Name: -
Synonym: has-circRNA_0046367
Host Gene: hsa-miR-34a
 
 
 
Disease basic information
DO ID:
 9452
DO name: fatty liver disease
Disease details: hepatic steatosis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PPARalpha
Associated microRNA: hsa-miR-34a
Biological function: -
Molecular mechanism: circRNA_0046367/hsa-miR-34a/PPARalpha regulatory system
Survival: -
Supported No.:
 1
Description:

These findings indicate a circRNA_0046367/miR-34a/PPARalpha regulatory system underlying hepatic steatosis. Normalized expression of circRNA_0046367 may ameliorate the lipoxidative stress on the basis of steatosis attenuation. circRNA_0046367, therefore, is suggested to be potential approach to the therapy of lipid peroxidative damage.
Other information
Title:

circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis.

Journal: Oxid Med Cell Longev
Published: 2017/10/12
PubMed ID: 29018509