circRNA basic information
circBase ID: hsa_circ_0001721
Name: hsa_circ_FAT1
Synonym: circFAT1
Host Gene: hsa-miR-4781-3p
 
 
 
Disease basic information
DO ID:
 0080001
DO name: bone disease
Disease details: osteogenic differentiation
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human periodontal ligament stem cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: hsa-miR-4781-3p
Biological function: circFAT1 does not affect the proliferation of PDLSCs. The osteogenic differentiation of PDLSCs was benefited from circFAT1
Molecular mechanism: circFAT1 serves as a miRNA sponge for hsa-miR-4781-3p targeting SMAD5.
Survival: -
Supported No.:
 1
Description:

circFAT1 might be considered as a potential target of PDLSCs mediated periodontal bone regeneration.
Other information
Title:

CircRNA FAT1 Regulates Osteoblastic Differentiation of Periodontal Ligament Stem Cells via miR-4781-3p/SMAD5 Pathway.

Journal: Stem Cells Int
Published: 2022/1/11
PubMed ID: 35003269