circRNA basic information
circBase ID: -
Name: hsa_circ_SH2B3
Synonym: circSH2B3
Host Gene: hsa-miR-4640-5P
 
 
 
Disease basic information
DO ID:
 1781
DO name: thyroid gland cancer
Disease details: thyroid cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: A normal thyroid follicular epithelial cell line (Nthy-ori 3-1), PTC cell lines (K1, BCPAP)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-4640-5P
Biological function: differentiation effect of AhR antagonist in PTC
Molecular mechanism: CircSH2B3 acted as an endogenous sponge of hsa-miR-4640-5p and modulated IGF2BP2 expression.
Survival: -
Supported No.:
 1
Description:

AhR antagonists promote differentiation of PTC via inhibiting the circSH2B3/miR-4640-5p/IGF2BP2 axis.
Other information
Title:

AhR Antagonist Promotes Differentiation of Papillary Thyroid Cancer via Regulating circSH2B3/miR-4640-5P/IGF2BP2 Axis.

Journal: Front Pharmacol
Published: 2022/1/11
PubMed ID: 35002727