circRNA basic information
circBase ID: -
Name: hsa_circ_CDK14
Synonym: CircCDK14
Host Gene: hsa-miR-3938
 
 
 
Disease basic information
DO ID:
0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: U87, U251, HEB cells
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-3938
Biological function: CircCDK14 promotes the migration, invasion and proliferation of glioma cells_n vitro_s well as tumorigenesis_n vivo.
Molecular mechanism: circCDK14 sponged hsa-miR-3938 to upregulate oncogenic gene PDGFRA expression.
Survival: poor
Supported No.:
1
Description:

circCDK14 induces tumor in glioma and increases malignant tumor behavior via the miR-3938/PDGFRA axis..

Other information
Title:

CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA.

Journal: Int J Biol Sci
Published: 2022/1/11
PubMed ID: 35002529