circRNA basic information
circBase ID: -
Name: hsa_circ_PVT1
Synonym: circPVT1
Host Gene: hsa-miR-203
 
 
 
Disease basic information
DO ID:
 365
DO name: bladder disease
Disease details: bladder outlet obstruction
Species: human
Species details: human
Sample type: PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-203
Biological function: circPVT1 knockdown alleviated BOO-induced bladder hypertrophy and fibrogenesis.
Molecular mechanism: circPVT1 sponges hsa-miR-203 and that the latter targets the 3-untranslated region of SOCS3
Survival: -
Supported No.:
 1
Description:

circPVT1 regulator of BOO-associated bladder wall remodeling and hypoxia-induced phenotypic changes in BMSCs by targeting the miR-203-SOCS3 signaling axis.
Other information
Title:

Circular RNA Plasmacytoma Variant Translocation 1 (CircPVT1) knockdown ameliorates hypoxia-induced bladder fibrosis by regulating the miR-203/Suppressor of Cytokine Signaling 3 (SOCS3) signaling axis.

Journal: Bioengineered
Published: 2022/1/11
PubMed ID: 35000524