circRNA basic information
circBase ID: hsa_circ_0001275
Name: hsa_circ_PLCL2
Synonym: circ_0001275
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: aged-matched LNCaP parental cells (Control), sub-lines displaying strong resistance (Clone 1), weak resistance (Clone 9) to enzalutamide.
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Our data suggest that increased levels of hsa_circ_0001275 contribute to enzalutamide resistance. hsa_circ_0001275 plasma expression showed a trend that mirrors the PSA level at specific disease time points, indicating that circRNAs mirror disease recurrence and burden and may be associated with enzalutamide resistance.
Other information
Title:

hsa_circ_0001275 Is One of a Number of circRNAs Dysregulated in Enzalutamide Resistant Prostate Cancer and Confers Enzalutamide Resistance In Vitro.

Journal: Cancers (Basel)
Published: 2021/12/25
PubMed ID: 34945002