circRNA basic information
circBase ID: hsa_circ_0076931
Name: hsa_circ_BAI3
Synonym: circ_0076931
Host Gene: hsa-miR-6760-3p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: H4, SK-N-MC, U118-MG, U251
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-6760-3p
Biological function: Overexpression of hsa_circ_0076931 inhibited proliferation, migration, and invasion while promoting apoptosis of glioma cells_n vitro, Overexpression of hsa_circ_0076931 inhibited progression of glioma in vivo
Molecular mechanism: Hsa_circ_0076931 stimulated CCBE1 expression by sponging hsa-miR-6760-3p,
Survival: -
Supported No.:
 1
Description:

The expression of miR-6760-3p and CCBE1 in hsa_circ_0076931-overexpressed tumors of BALB/C nude mice and glioma tissues and relevance to prognosis.
Other information
Title:

Hsa_circ_0076931 suppresses malignant biological properties, down-regulates miR-6760-3p through direct binding, and up-regulates CCBE1 in glioma.

Journal: Biosci Rep
Published: 2021/12/22
PubMed ID: 34931668