circRNA basic information
circBase ID: hsa_circ_0001879
Name: hsa_circ_NIPSNAP3A
Synonym: circ_0001879
Host Gene: hsa-miR-6873-5p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human umbilical vein endothelial cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-6873-5p
Biological function: Hsa_circ_0001879 inhibited the proliferation and migration ability of Human umbilical vein endothelial cells (HUVECs).
Molecular mechanism: Hsa_circ_0001879 directly bound to hsa-miR-6873-5p and acted as a sponge. hsa-miR-6873-5p-induced HDAC9 mRNA degradation was inhibited by hsa_circ_0001879.
Survival: -
Supported No.:
 1
Description:

hsa_circ_0001879 decreased the proliferation and migration of HUVECs by inhibiting miR-6873-5p-induced HDAC9 degradation.
Other information
Title:

Hsa_circ_0001879 promotes the progression of atherosclerosis by regulating the proliferation and migration of oxidation of low density lipoprotein (ox-LDL)-induced vascular endothelial cells via the miR-6873-5p-HDAC9 axis.

Journal: Bioengineered
Published: 2021/12/8
PubMed ID: 34872444