circRNA basic information
circBase ID: -
Name: hsa_circ_SLC7A11
Synonym: circSLC7A11
Host Gene: hsa-miR-330-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human HCC cell lines (HepG2, Hep3B, HCCLM3, Huh7, MHCC97H), immortalized hepatocyte cell line (WRL68)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-330-3p
Biological function: -
Molecular mechanism: -
Survival: poor
Supported No.:
 1
Description:

The acceleration of HCC progression and metastasis by circSLC7A11 through the circSLC7A11/miR-330-3p/CDK1 axis suggests that circSLC7A11 is a potential novel diagnostic and therapeutic target for HCC treatment.
Other information
Title:

The circular RNA circSLC7A11 functions as a mir-330-3p sponge to accelerate hepatocellular carcinoma progression by regulating cyclin-dependent kinase 1 expression.

Journal: Cancer Cell Int
Published: 2021/12/1
PubMed ID: 34844614