circRNA basic information
circBase ID: hsa_circ_0075001
Name: hsa_circ_NPM1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
9119
DO name: acute myeloid leukemia
Disease details: acute myeloid leukemia
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: NPM1
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
1
Description:

Hsa_circ_0075001 expression correlates positively with total NPM1 expression, but is independent of the NPM1 mutational status. High versus low hsa_circ_0075001 expression defines patient subgroups characterized by distinct gene expression patterns, such as lower expression of components of the Toll-like receptor signaling pathway in high hsa_circ_0075001 expression cases.

Other information
Title:

Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia.

Journal: Haematologica
Published: 2017/10/4
PubMed ID: 28971903