circRNA basic information
circBase ID: hsa_circ_0074032
Name: hsa_circ_SLC25A48
Synonym: circ_0074032
Host Gene: hsa-miR-198
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: RWEPE-1,LNCaPŁ¬PC-3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HOXA1
Associated microRNA: hsa-miR-198
Biological function: circ_0074032 silencing decreased xenograft tumour growth in vivo and induced cell apoptosis, curbed cell proliferation, migration and invasion in PCa cells in vitro.
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

The findings uncovered a novel mechanism by which circ_0074032 promoted PCa progression via elevating HOXA1 expression through acting as a miR-198 sponge, providing a mechanism for circ_0074032 to affect the development of PCa.
Other information
Title:

Hsa_circ_0074032 promotes prostate cancer progression through elevating homeobox A1 expression by serving as a microRNA-198 decoy.

Journal: Andrologia
Published: 2021/11/21
PubMed ID: 34799875