circRNA basic information
circBase ID: -
Name: hsa_circ_FNDC3B
Synonym: Circ-FNDC3B,
Host Gene: hsa-miR-143-3p
 
 
 
Disease basic information
DO ID:
 7693
DO name: abdominal aortic aneurysm
Disease details: abdominal aortic aneurysm
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human aortic VSMCs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ADAM10
Associated microRNA: hsa-miR-143-3p
Biological function: Silencing of circ-FNDC3B alleviates cell injury induced by Ang-II
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

circ-FNDC3B silencing ameliorated cytotoxicity triggered by Ang-II in VSMCs at least partially depending on the regulation of the miR-143-3p/ADAM10 axis.
Other information
Title:

Identification of Circ-FNDC3B, an Overexpressed circRNA in Abdominal Aortic Aneurysm, as a Regulator of Vascular Smooth Muscle Cells.

Journal: Int Heart J
Published: 2021/11/19
PubMed ID: 34789642