circRNA basic information
circBase ID: hsa_circ_0006352
Name: hsa_circ_SETDB1
Synonym: CircSETDB1
Host Gene: hsa-miR-129-3p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Procell (Wuhan, China) provided ovarian cancer cells (A2780, SKOV3), normal ovarian epithelial cells (IOSE-80), human embryonic kidney cells (293_). A2780, IOSE-80, 293_ cells as well as SKOV3 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAP3K3
Associated microRNA: hsa-miR-129-3p
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 3
Description:

CircSETDB1 silencing repressed SOC malignant progression through miR-129-3p/MAP3K3 pathway. This study supports circSETDB1 as a new therapeutic target for SOC.
Other information
Title:

CircSETDB1 knockdown inhibits the malignant progression of serous ovarian cancer through miR-129-3p-dependent regulation of MAP3K3.

Journal: J Ovarian Res
Published: 2021/11/19
PubMed ID: 34789310