circRNA basic information
circBase ID: -
Name: hsa_circ_SLC7A6
Synonym: CircSLC7A6
Host Gene: hsa-miR-107
 
 
 
Disease basic information
DO ID:
 2154
DO name: nephroblastoma
Disease details: wilms tumor
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human WT cell lines (HFWT, WiT49, 17_94), normal renal tubular epithelial cell line (HK-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ABL2
Associated microRNA: hsa-miR-107
Biological function: CircSLC7A6 knockdown inhibits the tumorigenesis of WT
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

It was the first time to determine the role of circSLC7A6 in WT, and we discovered that circSLC7A6 promoted WT progression via the miR-107/ABL2 axis, implying a novel and possible tactic for WT treatment.
Other information
Title:

CircSLC7A6 promotes the progression of Wilm tumor via microRNA-107/ ABL proto-oncogene 2 axis.

Journal: Bioengineered
Published: 2021/11/18
PubMed ID: 34787058