circRNA basic information
circBase ID: hsa_circ_0000729
Name: hsa_circ_GAS8
Synonym: circ_0000729
Host Gene: hsa-miR-1281
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: NSCLC cell lines (A549, NCI-H1650, NCI-H1299), human normal lung epithelial cell line (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXO3
Associated microRNA: hsa-miR-1281
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Knockdown of hsa_circ_0000729 inhibits the tumorigenesis of NSCLC through mediation of miR-1281/FOXO3 axis. Thus, hsa_circ_0000729 might be served as a crucial mediator in NSCLC.
Other information
Title:

Knockdown of hsa_circ_0000729 Inhibits the Tumorigenesis of Non-Small Cell Lung Cancer Through Mediation of miR-1281/FOXO3 Axis.

Journal: Cancer Manag Res
Published: 2021/11/18
PubMed ID: 34785952