circRNA basic information
circBase ID: -
Name: hsa_circ_PTCD3
Synonym: circPTCD3
Host Gene: hsa-miR-198
 
 
 
Disease basic information
DO ID:
1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal breast cell line (MCF-10a), breast cancer cell lines (MCF-7, BT474, MDA-MB-231, SKBr-3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-198
Biological function: CircPTCD3 Promoted the Proliferation and Migration of Breast Cancer Cells
Molecular mechanism: -
Survival: -
Supported No.:
1
Description:

To conclude, our findings shed light on the fact that circPTCD3 promotes the malignant behaviour of breast cancer by means of sponging miR-198, which indicates its potentiality to be a diagnostic or therapeutic target of breast cancer.

Other information
Title:

A Novel Circular RNA circPTCD3 Promotes Breast Cancer Progression Through Sponging miR-198.

Journal: Cancer Manag Res
Published: 2021/11/18
PubMed ID: 34785951