circRNA basic information
circBase ID: hsa_circ_0046600
Name: hsa_circ_B3GNTL1
Synonym: Circ_0046600
Host Gene: hsa-miR-1258
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human HCC cell lines (HCCLM3, MHCC97H, SNU-387, Huh-7), human liver epithelial cells (THLE-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SERBP1
Associated microRNA: hsa-miR-1258
Biological function: Circ_0046600 knockdown suppresses HCC cell growth and metastasis in vitro
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

Circ_0046600 promoted HCC progression via up-regulating SERBP1 through sequestering miR-1258; besides that, circ_0046600 was packaged into exosomes and could be released from HCC cells.
Other information
Title:

Circ_0046600 promotes hepatocellular carcinoma progression via up-regulating SERBP1 through sequestering miR-1258.

Journal: Pathol Res Pract
Published: 2021/11/17
PubMed ID: 34784519