circRNA basic information
circBase ID: hsa_circ_0067835
Name: hsa_circ_IFT80
Synonym: Circ-IFT80
Host Gene: hsa-miR-545-3p
 
 
 
Disease basic information
DO ID:
 1380
DO name: endometrial cancer
Disease details: endometrial cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human ECa cells (HEC-1B, EEC, Ishikawa), normal endometrial epithelial cells (human embryonic stem cell [hESC])
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FAM98A
Associated microRNA: hsa-miR-545-3p
Biological function: regulates the malignant phenotypes
Molecular mechanism: Silence of circ-IFT80 inhibits proliferation, migration, invasion and angiogenesis and triggers apoptosis in ECa cells
Survival: -
Supported No.:
 2
Description:

Circ-IFT80 may promote the malignant progression of ECa cells at least in part by modulating miR-545-3p/FAM98A axis, providing a potential therapeutic target for ECa.
Other information
Title:

Circular RNA intraflagellar transport 80 facilitates endometrial cancer progression through modulating miR-545-3p/FAM98A signaling.

Journal: J Gynecol Oncol
Published: 2021/11/17
PubMed ID: 34783205