circRNA basic information
circBase ID: -
Name: hsa_circ_PIP5K1A
Synonym: circPIP5K1A
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: YAP
Associated microRNA: hsa-miR-515-5p
Biological function: The depletion of circPIP5K1A by siRNA repressed osteosarcoma cell viabilities and induced osteosarcoma cell apoptosis. The suppression of circPIP5K1A attenuated the capabilities of invasion and migration of osteosarcoma cells.
Molecular mechanism: circPIP5K1A enhanced YAP expression by targeting hsa-miR-515-5p. hsa-miR-515-5p inhibited stemness of osteosarcoma cells
Survival: -
Supported No.:
 1
Description:

circular RNA circPIP5K1A contributed to cancer stemness of osteosarcoma by miR-515-5p/YAP axis.
Other information
Title:

Circular RNA circPIP5K1A contributes to cancer stemness of osteosarcoma by miR-515-5p/YAP axis.

Journal: J Transl Med
Published: 2021/11/15
PubMed ID: 34774083