circRNA basic information
circBase ID: -
Name: hsa_circ_CSPP1
Synonym: circCSPP1
Host Gene: hsa-miR-520h
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human prostate cancer cell lines (PC3, DU145, LNCaP), benign prostate hyperplasia cell line (BPH-1), human embryonic kidney cells (293T)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: EGR1
Associated microRNA: hsa-miR-520h
Biological function: the increased circCSPP1 significantly induced autophagy, which led to an enhanced potential in proliferation, migration, and invasion of prostate cancer cells
Molecular mechanism: circCSPP1 expression in prostate cancer cells was regulated by HnRNP-L
Survival: -
Supported No.:
 1
Description:

HnRNP-L-regulated circCSPP1/miR-520h/EGR1 axis modulates autophagy and promotes progression in prostate cancer.
Other information
Title:

HnRNP-L-regulated circCSPP1/miR-520h/EGR1 axis modulates autophagy and promotes progression in prostate cancer.

Journal: Mol Ther Nucleic Acids
Published: 2021/11/12
PubMed ID: 34760337