circRNA basic information
circBase ID: -
Name: hsa_circ_PDSS1
Synonym: circPDSS1
Host Gene: hsa-miR-502-3p, hsa-miR-4436a
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-502-3p, hsa-miR-4436a
Biological function: CircPDSS1 knockdown significantly inhibited the viability, clone formation ability and invasion ability of OS cells, and induced cell apoptosis
Molecular mechanism: circPDSS1 modulates OS cell functions by regulating the expression of hsa-miR-502-3p and hsa-miR-4436a
Survival: poor
Supported No.:
 1
Description:

circPDSS1 acts as a molecular sponge of miR-502-3p and miR-4436a regulates the proliferation and invasion of OS cells and promote the malignant progression of OS.
Other information
Title:

Circular RNA circPDSS1 promotes osteosarcoma progression by sponging miR-502-3p and miR-4436a.

Journal: Anticancer Drugs
Published: 2021/11/9
PubMed ID: 34744154