circRNA basic information
circBase ID: hsa_circ_0082374
Name: hsa_circ_CPA4
Synonym: circCPA4
Host Gene: hsa-miR-214-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TGIF2
Associated microRNA: hsa-miR-214-3p
Biological function: circCPA4 knockdown could suppress colony formation, migration, invasion, cell cycle progression, and expedite apoptosis of lung cancer cells in vitro
Molecular mechanism: circCPA4 could regulate TGIF2 expression by sponging hsa-miR-214-3p
Survival: -
Supported No.:
 2
Description:

CircCPA4 could act as a sponge of miR-214-3p to upregulate TGIF2 expression, thereby promoting the progression of lung cancer cells.
Other information
Title:

Circular RNA circCPA4 promotes tumorigenesis by regulating miR-214-3p/TGIF2 in lung cancer.

Journal: Thorac Cancer
Published: 2021/11/7
PubMed ID: 34741437