circRNA basic information
circBase ID: -
Name: hsa_circ_DLGAP4
Synonym: circDLGAP4
Host Gene: hsa-miR-503-3p
 
 
 
Disease basic information
DO ID:
 3526
DO name: cerebral infarction
Disease details: ischemic stroke
Species: human
Species details: human
Sample type: cell line
Sample type details: HCN-2 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: NEGR1
Associated microRNA: hsa-miR-503-3p
Biological function: CircDLGAP4 overexpression promoted cell viability and suppressed cell death and inflammatory cytokine concentrations in OGD-treated HCN-2 cells.
Molecular mechanism: CircDLGAP4 acted as the sponge for miR-503-3p and the impacts of circDLGAP4 overexpression on cell viability, death and inflammation in OGD-treated HCN-2 cells were reversed by miR-503-3p elevation.
Survival: -
Supported No.:
 1
Description:

CircDLGAP4 alleviated OGD-induced HCN-2 cell damage by regulating miR-503-3p/NEGR1 axis.
Other information
Title:

CircDLGAP4 overexpression relieves oxygen-glucose deprivation-induced neuronal injury by elevating NEGR1 through sponging miR-503-3p.

Journal: J Mol Histol
Published: 2021/11/6
PubMed ID: 34739656