circRNA basic information
circBase ID: -
Name: hsa_circ_RFX3
Synonym: CircRFX3
Host Gene: hsa-miR-1179, hsa-miR-1229
 
 
 
Disease basic information
DO ID:
0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: VASP
Associated microRNA: hsa-miR-1179, hsa-miR-1229
Biological function: Knockdown of circRFX3 suppressed glioma cell proliferation, migration and invasion and promoted apoptosis in vitro and repressed tumorigenesis of glioma in vivo
Molecular mechanism: via modulating hsa-miR-1179/hsa-miR-1229-VASP axis
Survival: -
Supported No.:
2
Description:

CircRFX3 served as a tumor promoter in glioma via modulating miR-1179/miR-1229-VASP axis.

Other information
Title:

CircRFX3 contributes to glioma progression through the circRFX3-miR-1179/miR-1229-VASP axis.

Journal: Cancer Cell Int
Published: 2021/11/4
PubMed ID: 34727925