circRNA basic information
circBase ID: hsa_circ_0103552
Name: hsa_circ_UBR1
Synonym: -
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CYR61
Associated microRNA: hsa-miR-515-5p
Biological function: circ_0103552 overexpression facilitated the multiplication, migration, and invasion of breast cancer cells, while knocking down circ_0103552 induced the opposite effects
Molecular mechanism: circ_0103552 could sponge hsa-miR-515-5p and restrained its expression in breast cancer cells
Survival: -
Supported No.:
 3
Description:

circ_0103552 up-modulates CYR61 expression by targeting miR-515-5p and thus facilitates the multiplication, migration, and invasion of breast cancer cells.
Other information
Title:

Circular RNA hsa_circ_0103552 Promotes Proliferation, Migration, and Invasion of Breast Cancer Cells through Upregulating Cysteine-Rich Angiogenic Inducer 61 (CYR61) Expression via Sponging MicroRNA-515-5p.

Journal: Tohoku J Exp Med
Published: 2021/10/29
PubMed ID: 34707022