circRNA basic information
circBase ID: -
Name: hsa_circ_NUDT21
Synonym: circNUDT21
Host Gene: hsa-miR-16-1-3p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MDM2/p53
Associated microRNA: hsa-miR-16-1-3p
Biological function: Overexpression and silencing of circNUDT21 promoted and inhibited, respectively, the proliferative and invasive abilities of BC cells
Molecular mechanism: circNUDT21 acted as a hsa-miR-16-1-3p sponge and that MDM2 was a potential downstream target of hsa-miR-16-1-3p
Survival: -
Supported No.:
 1
Description:

CircNUDT21 promoted BC progression by acting as a sponge of miR-16-1-3p to activate the miR-16-1-3p/MDM2/p53 axis.
Other information
Title:

circNUDT21 promotes bladder cancer progression by modulating the miR-16-1-3p/MDM2/p53 axis.

Journal: Mol Ther Nucleic Acids
Published: 2021/10/28
PubMed ID: 34703648