circRNA basic information
circBase ID: hsa_circ_0021735
Name: hsa_circ_CD44
Synonym: CircCD44
Host Gene: hsa-miR-502-5p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: IGF2BP2
Associated microRNA: hsa-miR-502-5p
Biological function: CircCD44 promotes TNBC proliferation, migration, invasion and tumorigenesis
Molecular mechanism: by sponging hsa-miR-502-5p and interacting with IGF2BP2
Survival: poor
Supported No.:
 2
Description:

CircCD44 promotes TNBC proliferation, migration, invasion and tumorigenesis at least partially by sponging miR-502-5p and interacting with IGF2BP2.
Other information
Title:

CircCD44 plays oncogenic roles in triple-negative breast cancer by modulating the miR-502-5p/KRAS and IGF2BP2/Myc axes.

Journal: Mol Cancer
Published: 2021/10/27
PubMed ID: 34696797