circRNA basic information
circBase ID: -
Name: hsa_circ_NEK6
Synonym: -
Host Gene: hsa-miR-382-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: BCAS2
Associated microRNA: hsa-miR-382-5p
Biological function: the silencing of circ_NEK6 could effectively suppress NSCLC cell proliferation, migration and invasion
Molecular mechanism: Circ_NEK6 sequestered hsa-miR-382-5p to fortify the expression of breast carcinoma amplified sequence 2 (BCAS2) in NSCLC
Survival: -
Supported No.:
 1
Description:

Circular RNA NEK6 contributes to the development of non-small-cell lung cancer by competitively binding with miR-382-5p to elevate BCAS2 expression at post-transcriptional level.
Other information
Title:

Circular RNA NEK6 contributes to the development of non-small-cell lung cancer by competitively binding with miR-382-5p to elevate BCAS2 expression at post-transcriptional level.

Journal: BMC Pulm Med
Published: 2021/10/20
PubMed ID: 34663267